中文同義詞:D(-)-蘇-1-對(duì)硝基基-2-二氯基-1,3-丙二醇;D-蘇-1-對(duì)硝基基-2-二氯乙酰氨基-1,3-丙二醇;左霉素;左旋霉素;D-蘇式-(-)-N-[alpha-(羥基甲基)-beta-羥基-對(duì)硝基乙基]-2,2-二氯; 雜質(zhì)D
英文名稱:Chloramphenicol
英文同義詞:[theta-(theta,theta)]-;[R-(R*,R*)]-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]ethanamide;2,2-dichloro-n-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-acetamid;2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-,[R-(R*,R*)]-Acetamide;2,2-dichloro-n-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-acetamid;Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl);Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-;Acetamide, 2,2-dichloro-N-[beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-
CAS號(hào): 56-75-7
分子式:C11H12Cl2N2O5
分子量:323.13
EINECS號(hào):200-287-4
化學(xué)性質(zhì):白色或微黃帶綠色針狀結(jié)晶。熔點(diǎn)150.5-151.5℃(149.7-150.7℃)。在高真空下可以升華。微溶于水(2.5mg/ml,25℃),略溶于丙二醇(150.8mg/ml),易溶于甲醇、、丁醇、乙酯,不溶于、石油醚,植物油。味極苦。
用途:屬廣譜抑菌抗生素,是治療傷寒,副傷寒的藥,治療厭氧菌感染的藥物之一,其次用于敏感微生物所致的各種感染性疾病的治療。由于不良反應(yīng)嚴(yán)重現(xiàn)用得越來越少。
包裝:25KG/紙板桶
生產(chǎn)方法:各國對(duì)氯霉素的生產(chǎn)方法進(jìn)行過大量的研究,歸納起來有:(1)對(duì)硝基乙酮法;(2)乙烯法;(3)肉桂醇法;(4)對(duì)硝基肉桂醇法;(5)對(duì)硝基甲醛法。我國采用對(duì)硝基乙酮法,該法由乙經(jīng)硝化、氧化、溴化、成鹽、水解、乙?;?、加成、還原、分解、分拆、二氯乙?;寐让顾亍?
◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆◆ |
[供] Diclofenac sodium 15307-79-6 |
[供]二甲酰酒石酸 Dibenzoyltartaric acid 62708-56-9 |
[供] Ketoconazole 65277-42-1 |
[供]阿司匹林 Acetylsalicylic acid 50-78-2 |
[供]硝酸 Miconazole nitrate 22832-87-7 |
[供]二鈉 Adenosine 5'-triphosphate disodium salt 51963-61-2 |
[供]氟比洛芬 (R)-2-Flurbiprofen 51543-40-9 |
[供] Paclitaxel 33069-62-4 |
[供] Anastrozole 120511-73-1 |
[供]卡巴他賽 Cabazitaxel 183133-96-2 |
[供]側(cè)鏈 949023-16-9 |
[供]多烯 Docetaxel 114977-28-5 |
[供]冬凌草甲素 Oridonin 28957-04-2 |
[供]側(cè)鏈 949023-16-9 |
[供] Neomycin sulfate 1405-10-3 |
[供]雙氯芬酸二乙胺鹽 Diclofenac diethylamine 78213-16-8 |
[供] Ambroxol hydrochloride 23828-92-4 |
[供] Beclomethasone dipropionate 5534-09-8 |
[供]紅霉素 Erythromycin 114-07-8 |
[供]葡醛內(nèi)酯 D-GLUCURONO-3,6-LACTONE 32499-92-6 |
[供]左旋肉堿酒石酸鹽 L-Carnitine-L-tartrate 36687-82-8 |
[供] Inosine 58-63-9 |
[供] Rutin 153-18-4 |
[供]枸櫞酸(三氧胺)Tamoxifen citrate 54965-24-1 |
[供]羥丙基-β-環(huán)糊精 Hydroxypropyl-beta-cyclodextrin 94035-02-6 |